Altered Spontaneous Brain Activity Within Schizophreni A...

Research Article: Altered Spontaneous Brain Activity in Schizophrenia: A Meta-Analysis and a Large-Sample Study (This Article was Okayed by Professor Michael Christie on May 2, 2016) Introduction Schizophrenia is a neuropsychiatric disorder (Xu, Y., Zhuo., Qin, W., Zhu, J., Yu, C. (2015) page one). This disorder has been known to have structural and functional abnormalities that affect the brain (Xu, Y., Zhuo., Qin, W., Zhu, J., Yu, C. (2015) page one). Individuals with schizophrenia suffer from spontaneous brain activity (Xu, Y., Zhuo., Qin, W., Zhu, J., Yu, C. (2015) page one). Amplitude of low frequency fluctuations (ALFF), fractional ALFF (fALFF), and regional homogeneity (ReHo) of blood-oxygen-level-dependent (BLOD) signals that come from resting-state functional magnetic resonance imaging (rs-fMRI) is how spontaneous brain activity is measured (Xu, Y., Zhuo., Qin, W., Zhu, J., Yu, C. (2015) page one). Amplitude of low frequency fluctuations (ALFF) is used to measure the blood-oxygen-level-dependent (BOLD). This happens by a low frequency range at a single-voxel level (Xu, Y., Zhuo., Qin, W., Zhu, J., Yu, C. (2015) page one). The fractional Amplitude in a low ampli tude in the frequency bands as a total (Xu, Y., Zhuo., Qin, W., Zhu, J., Yu, C. (2015) page one). The regional homogeneity (ReHo) is used to measure how similar in time are the blood-oxygen-level-dependent (BOLD) are (Xu, Y., Zhuo., Qin, W., Zhu, J., Yu, C. (2015) page one). This article talks